What is testosterone pellet therapy?

Testosterone pellet therapy delivers hormones through small subdermal pellets, typically about the size of a grain of rice, that are surgically placed under the skin to provide consistent hormone levels over time. The pellets are composed of crystalline testosterone compressed into solid form and are implanted in a simple office procedure, usually in the upper buttock or hip area under local anesthetic.

Once inserted, the pellets release testosterone gradually through a process of diffusion and metabolism. The hormone enters the bloodstream steadily rather than in peaks and valleys, which distinguishes pellet therapy from other delivery methods. Most pellets remain active for three to six months, though duration can vary based on the specific formulation, individual metabolism, and dosage strength. Patients typically require new pellets inserted every three to four months to maintain therapeutic hormone levels.

This method appeals to patients seeking a set-and-forget approach to hormone replacement, as it does not require daily pills, weekly injections, or frequent clinic visits for application. The subdermal placement also means there is no cream or gel residue on the skin. Providers specializing in hormone replacement therapy can evaluate whether pellet therapy aligns with individual health goals and medical history.